(MENAFN- GlobeNewsWire - Nasdaq) Smith+Nephew (LSE:SN, NYSE:SNN), the global medical technology company, today announces the review of medical technologies guidance from the UK National Institute for health and Care Excellence (NICE) for its PICO Single Use Negative Pressure Wound Therapy System (sNPWT).
NICE have reviewed 'Medical Technology Guideline 43 PICO negative pressure wound dressings for closed surgical incisions' which recognises that Smith+Nephew's PICO sNPWT provides better clinical outcomes than standard dressings in patients at high risk of surgical site infections (SSIs), at similar overall cost. As a result, NICE has reconfirmed its guidance, that PICO sNPWT should be considered as an option for closed surgical incisions in patients who are at high risk of surgical site infections,1 remains the same. Key high risk factors include a high body mass index (BMI), diabetes, renal insufficiency and smoking among others.2
In the recent NICE review, a total of 28 papers published after the original guidance were identified. These included 12 Randomised Control Trials (RCT), 1 Uncontrolled Randomised Trial, 8 cohort studies, 3 before and after studies, and 4 economic studies. The 24 clinical studies included a total of 7,790 patients with PICO sNPWT being used in 3,754.
NICE concluded that PICO sNPWT is associated with fewer SSIs and seromas compared with standard wound dressings. Cost modelling suggests that compared with standard wound dressings, PICO sNPWT provides extra clinical benefits at similar overall cost to the NHS.1 For some types of surgery, such as colorectal, cardiothoracic and vascular surgery PICO sNPWT provides cost savings.1
The PICO sNPWT dressing includes a proprietary AIRLOCK◊ Technology layer that delivers negative pressure wound therapy across a surgical incision and the surrounding zone of injury.3,4 This unique feature is designed to help reduce the risk of wound complications by reducing post-operative fluid5,6 and tension*7 around a closed surgical incision. The combination of these actions helps reduce the risk of two common surgical site complications - surgical wound dehiscence and --
“It's fitting that this recognition from NICE occurs during International Cesarean Awareness Month, as PICO sNPWT has been shown to help reduce the risk of SSI's for high-risk C-section patients,**9-11 said Simon Tarry, Senior Vice President and General Manager, Advanced Wound Management for International Markets at Smith+Nephew.“PICO sNPWT provides significant productivity opportunities for healthcare systems, and improved outcomes for patients. We hope this recognition will help Smith+Nephew support our customers to achieve a new standard of care to reduce the growing burden of wound care on patients and health care professionals.”
To learn more about the NICE recommendations and PICO sNPWT please visit:
- ends –
Enquiries
Media
Dave Snyder +1 (978) 749-1440
Smith+Nephew
* as demonstrated in biomechanical modelling
** compared to conventional dressings/standard care
References
NICE Medical Technology Guidance MTG43. PICO Negative Pressure Wound Dressings for closed surgical incisions. May 9th 2019
World Union of Wound Healing Societies (WUWHS) Consensus Document. Closed surgical incision management: understanding the role of NPWT. Wounds International, 2016
Casey C. Consistent delivery of therapeutic negative pressure levels by a single use negative pressure wound therapy system (sNPWT)* in a wound model. Paper presented at: EWMA; 2019; Gothenburg, Sweden.
Smith+Nephew 2021TM Pressure Mapping Study. Internal Report. DS/19/211/R - Part B.
Karlakki SL, Hamad AK, Whittall C, et al negative pressure wound therapy dressings (iNPWTd) in routine primary hip and knee arthroplasties: A randomised controlled trial. Bone Joint Res. 2016;5(8):328-337.
Payne C, Edwards D.Application of the Single Use Negative Pressure Wound Therapy Device ( PICO ) on a Heterogeneous Group of Surgical and Traumatic Wounds. ePlasty. 2014:152-166.
Loveluck J, Copeland, T., Hill, J., Hunt, A., and Martin, R., .Biomechanical Modeling of the Forces Applied to Closed Incisions During Single-Use Negative Pressure Wound Therapy. ePlasty. 2016.
Saunders C, Nherera LM, Horner A, Trueman P. Single-Use negative-pressure wound therapy versus conventional dressings for closed surgical incisions: systematic literature review and meta-analysis. BJS Open. 2021;0(0):1 - 8
Hyldig N, Vinter CA, Kruse M, et al. Prophylactic incisional negative pressure wound therapy reduces the risk of surgical site infection after caesarean section in obese women: A pragmatic randomised clinical trial. BJOG. 2019;126:628-635.
Saunders C, et al. A single use negative pressure system reduces surgical site complications compared with conventional dressings in closed surgical incisions: a systematic literature review with meta-analysis. Poster presented at the European Wound Management Association annual meeting, June 5-7, 2019, Gothenburg, Sweden.
NICE (2019) PICO negative pressure wound dressings for closed surgical incisions [online] accessible from: [Last accessed: Sept 2023]
About Smith+Nephew
Smith+Nephew is a portfolio medical technology business focused on the repair, regeneration and replacement of soft and hard tissue. We exist to restore people's bodies and their self-belief by using technology to take the limits off living. We call this purpose 'Life Unlimited'. Our 18,000 employees deliver this mission every day, making a difference to patients' lives through the excellence of our product portfolio, and the invention and application of new technologies across our three global business units of Orthopaedics, Sports Medicine & ENT and Advanced Wound Management.
Founded in Hull, UK, in 1856, we now operate in more than 100 countries, and generated annual sales of $5.5 billion in 2023. Smith+Nephew is a constituent of the FTSE100 (LSE:SN, NYSE:SNN). The terms 'Group' and 'Smith+Nephew' are used to refer to Smith & Nephew plc and its consolidated subsidiaries, unless the context requires otherwise.
For more information about Smith+Nephew, please visit and follow us on X , LinkedIn , Instagram or Facebook .
Forward-looking Statements
This document may contain forward-looking statements that may or may not prove accurate. For example, statements regarding expected revenue growth and trading profit margins, market trends and our product pipeline are forward-looking statements. Phrases such as "aim", "plan", "intend", "anticipate", "well-placed", "believe", "estimate", "expect", "target", "consider" and similar expressions are generally intended to identify forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and other important factors that could cause actual results to differ materially from what is expressed or implied by the statements. For Smith+Nephew, these factors include: conflicts in Europe and the Middle East, economic and financial conditions in the markets we serve, especially those affecting healthcare providers, payers and customers; price levels for established and innovative medical devices; developments in medical technology; regulatory approvals, reimbursement decisions or other government actions; product defects or recalls or other problems with quality management systems or failure to comply with related regulations; litigation relating to patent or other claims; legal and financial compliance risks and related investigative, remedial or enforcement actions; disruption to our supply chain or operations or those of our suppliers; competition for qualified personnel; strategic actions, including acquisitions and disposals, our success in performing due diligence, valuing and integrating acquired businesses; disruption that may result from transactions or other changes we make in our business plans or organisation to adapt to market developments; relationships with healthcare professionals; reliance on information technology and cybersecurity; disruptions due to natural disasters, weather and climate change related events; changes in customer and other stakeholder sustainability expectations; changes in taxation regulations; effects of foreign exchange volatility; and numerous other matters that affect us or our markets, including those of a political, economic, business, competitive or reputational nature. Please refer to the documents that Smith+Nephew has filed with the U.S. Securities and Exchange Commission under the U.S. Securities Exchange Act of 1934, as amended, including Smith+Nephew's most recent annual report on Form 20-F, which is available on the SEC's website at sec, for a discussion of certain of these factors. Any forward-looking statement is based on information available to Smith+Nephew as of the date of the statement. All written or oral forward-looking statements attributable to Smith+Nephew are qualified by this caution. Smith+Nephew does not undertake any obligation to update or revise any forward-looking statement to reflect any change in circumstances or in Smith+Nephew's expectations.
◊ Trademark of Smith+Nephew. Certain marks registered in US Patent and Trademark Office 42690 GLOBAL
MENAFN04042024004107003653ID1108059744