Creative Biolabs Launches Its Optimal Phage Library Screening Service
Phage display is a powerful laboratory technique widely used for the study of protein-protein, protein-peptide and protein-DNA interactions. Specifically, after the gene coding proteinsis inserted into a phage coat protein gene, the phage 'displaysthe protein on its outside while the protein gene remains inside, thereby resulting in a connection between genotype and phenotype. The displayed phages can be screened against other proteins, peptide or DNA sequences, so as to detect interaction between the displayed protein and other molecules. Hence, phage library screening has been considered an extremely useful technique for the enrichment and identification of binders with high affinity and specificity in libraries of interest.
'Phage display technology has emerged as one of the principal approaches applied to a wide range of protein interaction studies, particularly to the discovery of specific antibodies, scaffolds or ligands.That's why we value this technology very much. Through years of development, our display service makes it possible to makebiopanning strategiestailored to the clients'diverse requirements. Generally, weare able toselect scFvor Fab antibodies with the affinity of 10-7. Besides, thesub-libraries of the isolated scFvor Fab antibodiesenable us to increase the affinity from 10-8to 10-9. So far, our companyhas managed toobtain a scFv antibody with anaffinity of up to 10-12.There exist several methods for library screening. The most common approach is solid-phase screening, adopted to select binders against specific targets adsorbed onto a solid surface. Solution-sorting screening serves as an ideal approach to antibody selection, and cell-base screening finds its use particularly in cell surface antigen selection. In a word, many approaches have been available here to fulfill a variety of market demands,a scientist from Creative Biolabs said.In order to optimize itsphage display library screening service, the company also offers proprietary phage display libraries. Its phage library construction portfolio covers the scaffold library, naïve or semi-syntheticpeptide library, cDNA library, etc.To sum up, it offers a comprehensive list of phage display libraries to improve its phage library screening service. Thus, there's every reason to believe that its screening service will satisfy different requirements of its customers for biopanning.
About Creative BiolabsCreative Biolabs is a leading custom service provider, with abundant experience in antibody production and engineering. Its service covers murine, human, monkey, rabbit, chicken, dog, llama and camel monoclonal antibody production. The company also conductsin-depth antibody humanization and affinity maturation using phage display and DNA mutagenesis approaches.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-619-7922
Address:45-1 Ramsey Road
City: Shirley
State: New York
Country: United States
Website: www.creative-biolabs.com/
Legal Disclaimer:
MENAFN provides the
information “as is” without warranty of any kind. We do not accept
any responsibility or liability for the accuracy, content, images,
videos, licenses, completeness, legality, or reliability of the information
contained in this article. If you have any complaints or copyright
issues related to this article, kindly contact the provider above.

Comments
No comment