
Bronchiectasis Pipeline 2025: Comprehensive Clinical Trials And Therapies Analysis With Key MOA And ROA Insights By Delveinsight Solaeromed, Insmed, Novabiotics Ltd, Synspira Therapeutics, Parion

(Las Vegas, Nevada, United States) As per DelveInsight's assessment, globally, Bronchiectasis pipeline constitutes 15+ key companies continuously working towards developing 15+ Bronchiectasis treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.
“Bronchiectasis Pipeline Insight, 2025 " report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Bronchiectasis Market.
The Bronchiectasis Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.
Some of the key takeaways from the Bronchiectasis Pipeline Report:
Companies across the globe are diligently working toward developing novel Bronchiectasis treatment therapies with a considerable amount of success over the years.
Bronchiectasis companies working in the treatment market are SolAeroMed, Insmed, NovaBiotics Ltd, Synspira Therapeutics, Parion Sciences, Chiesi Farmaceutic, CSL Behring, Haisco Pharmaceutical, SolAeroMed Inc., AstraZeneca, Zambon SpA, Boehringer Ingelheim, Armata Pharmaceuticals, Renovion, and others, are developing therapies for the Bronchiectasis treatment
Emerging Bronchiectasis therapies in the different phases of clinical trials are- S1226, Brensocatib, P339, Research Programme:NCFB, Research programme: mucolytic agents, CHF 6333, CSL787, HSK31858, S-1226, Benralizumab, Colistimethate sodium, BI 1291583, AP-PA02, ARINA-1, and others are expected to have a significant impact on the Bronchiectasis market in the coming years.
In August 2025, The FDA has approved brensocatib (Brinsupri; Insmed) for the treatment of non–cystic fibrosis bronchiectasis, marking it as the first approved therapy for this patient group and the first dipeptidyl peptidase 1 (DPP1) inhibitor authorized for a neutrophil-driven disease. Brensocatib is an oral, small-molecule, reversible DPP1 inhibitor that blocks DPP1, reducing the activation of neutrophil serine proteases, which play a central role in inflammation and tissue damage in chronic lung diseases such as bronchiectasis.
In February 2025, The FDA assigned priority review to brensocatib, an investigational therapy for patients with non-cystic fibrosis bronchiectasis. After the new drug application was accepted, the target action date was scheduled for August 12, 2025. If approved, brensocatib would be the first approved treatment for bronchiectasis and the inaugural drug in the dipeptidyl peptidase 1 class for neutrophil-driven diseases.
In February 2025, Verona Pharma is a biopharmaceutical company focused on creating and commercializing innovative therapies for chronic respiratory diseases with significant unmet needs. Its first commercial product, Ohtuvayre (ensifentrine), is the first inhaled maintenance therapy for COPD that uniquely combines bronchodilator and non-steroidal anti-inflammatory effects in one molecule. Ensifentrine also holds promise for treating non-cystic fibrosis bronchiectasis, cystic fibrosis, asthma, and other respiratory disorders.
Bronchiectasis Overview
Bronchiectasis is a chronic lung condition characterized by permanent widening and damage of the airways (bronchi), leading to mucus buildup, frequent lung infections, coughing, and difficulty breathing. It often results from infections, genetic disorders like cystic fibrosis, or conditions that impair the lungs' ability to clear mucus. Early management can help reduce complications and improve quality of life.
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Emerging Bronchiectasis Drugs Under Different Phases of Clinical Development Include:
S1226: SolAeroMed
Brensocatib: Insmed
NP339: NovaBiotics Ltd
Research Programme:NCFB: Synspira Therapeutics
Research programme: mucolytic agents: Parion Sciences
CHF 6333: Chiesi Farmaceutic
CSL787: CSL Behring
HSK31858: Haisco Pharmaceutical
S-1226: SolAeroMed Inc.
Benralizumab: AstraZeneca
Colistimethate sodium: Zambon SpA
BI 1291583: Boehringer Ingelheim
AP-PA02: Armata Pharmaceuticals
ARINA-1 : Renovion
Bronchiectasis Route of Administration
Bronchiectasis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
Oral
Parenteral
Intravenous
Subcutaneous
Topical
Bronchiectasis Molecule Type
Bronchiectasis Products have been categorized under various Molecule types, such as
Monoclonal Antibody
Peptides
Polymer
Small molecule
Gene therapy
Bronchiectasis Pipeline Therapeutics Assessment
Bronchiectasis Assessment by Product Type
Bronchiectasis By Stage and Product Type
Bronchiectasis Assessment by Route of Administration
Bronchiectasis By Stage and Route of Administration
Bronchiectasis Assessment by Molecule Type
Bronchiectasis by Stage and Molecule Type
DelveInsight's Bronchiectasis Report covers around 15+ products under different phases of clinical development like
Late-stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I)
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Route of Administration
Further Bronchiectasis product details are provided in the report. Download the Bronchiectasis pipeline report to learn more about the emerging Bronchiectasis therapies
Some of the key companies in the Bronchiectasis Therapeutics Market include:
Key companies developing therapies for Bronchiectasis are - Zambon, Boehringer Ingelheim, SolAeroMed, Insmed Incorporated, Chiesi Farmaceutici, Renovion, Haisco Pharmaceutical, Armata Pharmaceuticals, AstraZeneca, CSL Behring, and others.
Bronchiectasis Pipeline Analysis:
The Bronchiectasis pipeline report provides insights into
The report provides detailed insights about companies that are developing therapies for the treatment of Bronchiectasis with aggregate therapies developed by each company for the same.
It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Bronchiectasis Treatment.
Bronchiectasis key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
Bronchiectasis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Bronchiectasis market.
The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
Download Sample PDF Report to know more about Bronchiectasis drugs and therapies
Bronchiectasis Pipeline Market Drivers
Increasing prevalence of bronchiectasis worldwide, particularly among aging populations
Rising awareness and improved diagnosis of the disease
Advancements in novel therapies targeting underlying causes and inflammation
Growing investment in research and development by pharmaceutical companies
Expansion of clinical trials exploring innovative drug candidates
Bronchiectasis Pipeline Market Barriers
High costs associated with drug development and clinical trials
Complexity of the disease with heterogeneous patient populations
Limited efficacy of some current therapeutic options in advanced cases
Stringent regulatory requirements for approval of new treatments
Challenges in patient recruitment for clinical trials
Scope of Bronchiectasis Pipeline Drug Insight
Coverage: Global
Key Bronchiectasis Companies: SolAeroMed, Insmed, NovaBiotics Ltd, Synspira Therapeutics, Parion Sciences, Chiesi Farmaceutic, CSL Behring, Haisco Pharmaceutical, SolAeroMed Inc., AstraZeneca, Zambon SpA, Boehringer Ingelheim, Armata Pharmaceuticals, Renovion, and others
Key Bronchiectasis Therapies: S1226, Brensocatib, P339, Research Programme:NCFB, Research programme: mucolytic agents, CHF 6333, CSL787, HSK31858, S-1226, Benralizumab, Colistimethate sodium, BI 1291583, AP-PA02, ARINA-1, and others
Bronchiectasis Therapeutic Assessment: Bronchiectasis current marketed and Bronchiectasis emerging therapies
Bronchiectasis Market Dynamics: Bronchiectasis market drivers and Bronchiectasis market barriers
Request for Sample PDF Report for Bronchiectasis Pipeline Assessment and clinical trials
Table of Contents
1. Bronchiectasis Report Introduction
2. Bronchiectasis Executive Summary
3. Bronchiectasis Overview
4. Bronchiectasis- Analytical Perspective In-depth Commercial Assessment
5. Bronchiectasis Pipeline Therapeutics
6. Bronchiectasis Late Stage Products (Phase II/III)
7. Bronchiectasis Mid Stage Products (Phase II)
8. Bronchiectasis Early Stage Products (Phase I)
9. Bronchiectasis Preclinical Stage Products
10. Bronchiectasis Therapeutics Assessment
11. Bronchiectasis Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Bronchiectasis Key Companies
14. Bronchiectasis Key Products
15. Bronchiectasis Unmet Needs
16 . Bronchiectasis Market Drivers and Barriers
17. Bronchiectasis Future Perspectives and Conclusion
18. Bronchiectasis Analyst Views
19. Appendix
20. About DelveInsight
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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