(MENAFN- GlobeNewsWire - Nasdaq) SOMERVILLE, Mass., Nov. 03, 2025 (GLOBE NEWSWIRE) -- Tessera Therapeutics, the biotechnology company pioneering a new approach in genetic medicine known as Gene WritingTM, today announced three presentations of new preclinical data at the upcoming American Society of Hematology (ASH) Annual Meeting taking place in Orlando, Florida, December 6 – 9, 2025.

“The data we're presenting at this year's ASH meeting reflect the strong momentum of our in vivo programs for sickle cell disease (SCD) and T-cell engineering,” said Michael Severino, M.D., CEO of Tessera Therapeutics.“We look forward to sharing new in vivo editing data from our SCD and CAR-T programs and remain deeply committed to advancing our Gene Writing and delivery platforms to develop transformative therapies for patients.”

Details of the Company's 67^th ASH Annual Meeting presentations are as follows:

Poster Presentations:

• Title: In Vivo Correction of the Sickle Cell Disease Mutation in Hematopoietic Stem Cells Using RNA Gene Writers
• Poster board #: 2536
• Session: 801. Gene Therapies: Poster I
• Presenter: Yaser Heshmati, Ph.D.
• Session Date and Time: December 6, 2025, 5:30 p.m. – 7:30 p.m. EST
• Location: Orange County Convention Center, West Halls B3-B4
  
• Title: In Vivo RNA Delivery by Targeted Lipid Nanoparticles Enable Gene Editing in Hematopoietic Stem Cells and T Cells
• Poster board #: 4318
• Session: 801. Gene Therapies: Poster II
• Presenter: Rahul Palchaudhuri, Ph.D.
• Session Date and Time: December 7, 2025, 6:00 p.m. – 8:00 p.m. EST
• Location: Orange County Convention Center, West Halls B3-B4
  
• Title: Targeted LNP Delivery of an RNA Gene Writer In Vivo Enables Generation of Functional CAR-T Cells
• Poster board #: 6097
• Session: 801. Gene Therapies: Poster III
• Presenter: Cecilia Cotta-Ramusino, Ph.D.
• Session Date and Time: December 8, 2025, 6:00 p.m. – 8:00 p.m. EST
• Location: Orange County Convention Center, West Halls B3-B4

About Tessera Therapeutics

Tessera Therapeutics is pioneering a new approach to genome engineering through the development of its Gene WritingTM and delivery platforms, with the aim to unlock broad new therapeutic frontiers. Our Gene Writing platform is designed to write therapeutic messages into the genome by efficiently changing single or multiple DNA base pairs, precisely correcting insertions and deletions, or adding exon-length sequences and whole genes. Our proprietary lipid nanoparticle delivery platform is designed to enable the in vivo delivery of RNA to targeted cell types. We believe our Gene Writing and delivery platforms will enable transformative genetic medicines to not only cure diseases that arise from errors in a single gene, but also modify inherited risk factors for common diseases and create engineered cells to treat cancer and potentially autoimmune and other diseases. Tessera Therapeutics was founded in 2018 by Flagship Pioneering, a life sciences innovation enterprise that conceives, creates, resources, and develops first-in-category bioplatform companies to transform human health and sustainability.

For more information about Tessera, please visit

Contact

Jonathan Pappas
LifeSci Communications, LLC
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