(MENAFN- GlobeNewsWire - Nasdaq) Blepharitis, a prevalent chronic inflammatory eye condition, impacts the eyelid margins and is classified as anterior or posterior blepharitis. Key market drivers include a growing patient pool, aging populations, and rising dry eye syndrome diagnoses. Over 30% of ophthalmology patients show blepharitis signs, highlighting its commonality. The aging population's increase in meibomian gland dysfunction fuels treatment demand. However, the absence of FDA-approved medications limits treatment standardization. Significant opportunities exist for disease-modifying therapies targeting blepharitis's root causes, as innovation in anti-inflammatory formulations and biologics emerges.

Dublin, Nov. 19, 2025 (GLOBE NEWSWIRE) -- The "Blepharitis Market - A Global and Regional Analysis: Focus on Regional and Country Analysis - Analysis and Forecast, 2025-2035" report has been added to ResearchAndMarkets's offering.
The key drivers propelling the blepharitis market include a large and growing patient pool with a chronic disease profile, an expanding geriatric population, and an increase in dry eye disease diagnoses. Blepharitis is one of the most commonly diagnosed ocular conditions. Epidemiological data indicate that over 30% to 50% of ophthalmology patients exhibit signs of blepharitis. For instance, in the U.S., the American Academy of Ophthalmology reports that millions of annual ophthalmic visits involve lid margin inflammation, often co-existing with dry eye syndrome. Rising awareness driven by digital eye strain, aging populations, and cosmetic uses is prompting more patients to seek diagnosis and treatment.
Furthermore, age-related meibomian gland dysfunction, a key contributor to posterior blepharitis, is on the rise. The World Health Organization projects that the global population aged 60 years and above will double by 2050. This demographic shift directly correlates with a growing demand for chronic blepharitis therapies, particularly among cataract patients and contact lens users, two high-risk groups for MGD-related symptoms.
Moreover, as blepharitis often coexists with dry eye disease, the drug market benefits from this comorbidity. Companies are increasingly bundling or co-marketing anti-inflammatory eye drops, tear supplements, and lid hygiene solutions under a multi-symptom management strategy.
However, the blepharitis market continues to face significant challenges due to the absence of FDA-approved medications specifically indicated for the condition. This regulatory gap not only limits the development of standardized treatment protocols but also complicates reimbursement, thereby discouraging pharmaceutical investment in a condition with otherwise strong therapeutic demand. In clinical practice, erythromycin ointment is frequently prescribed for blepharitis; however, its official approval is limited to bacterial conjunctivitis. As a result, its use in blepharitis remains off-label, leading to variability in prescribing behavior and reduced inclusion in formulary listings, ultimately affecting both access and treatment outcomes.
Compounding this issue is the market's saturation with low-cost generic drugs, particularly macrolide antibiotics and corticosteroids, which dominate current treatment regimens. These legacy drugs are often used in off-label combinations and are favored for their affordability, but they offer limited innovation or specificity for blepharitis.
There is a significant opportunity in the blepharitis market for developing disease-modifying therapies (DMTs) that address the root causes of the condition, such as inflammation and meibomian gland dysfunction, without relying on steroids or antibiotics. These targeted treatments could reduce recurrence and improve long-term outcomes. Companies are expanding their pipelines to include anti-inflammatory formulations for ocular surface diseases, including blepharitis. Simultaneously, research into novel biologics and small molecules such as cytokine inhibitors and lipid modulators is gaining traction. This innovation wave reflects a broader shift toward precision medicine and chronic-care solutions in ophthalmology.
Key Topics Covered:
Executive Summary
Scope and Definition
Market/Product Definition
Key Questions Answered
Analysis and Forecast Note
1. Global Blepharitis Market: Industry Outlook
1.1 Market Overview
1.2 Epidemiological Analysis of Blepharitis, By Region
1.3 Regulatory Landscape of Blepharitis Market
1.4 Key Trends
1.5 Clinical Trial Analysis
1.6 Market Dynamics
1.6.1 Impact Analysis
1.6.2 Market Drivers
1.6.3 Market Restraint
1.6.4 Market Opportunities
2. Global Blepharitis Market, by Region, $Million, 2023-2035
2.1 North America
2.1.1 Market Dynamics
2.1.2 Market Sizing and Forecast
2.1.2.1 North America Blepharitis Market, by Country
2.1.2.1.1 U.S.
2.2 Europe
2.2.1 Market Dynamics
2.2.2 Market Sizing and Forecast
2.2.2.1 Europe Blepharitis Market, by Country
2.2.2.1.1 Germany
2.2.2.1.2 U.K.
2.2.2.1.3 France
2.2.2.1.4 Italy
2.2.2.1.5 Spain
2.3 Asia-Pacific
2.3.1 Market Dynamics
2.3.2 Market Sizing and Forecast
2.3.2.1 Asia-Pacific Blepharitis Market, by Country
2.3.2.1.1 Japan
2.4 Rest-of-the-World
2.4.1 Market Dynamics
2.4.2 Market Sizing and Forecast
3. Global Blepharitis Market: Competitive Landscape and Company Profiles
3.1 Key Developments and Strategies
3.1.1 Funding Activities
3.1.2 Mergers and Acquisitions
3.1.3 Regulatory Approvals
3.1.4 Partnerships, Collaborations and Business Expansions
3.2 Company Profiles
3.2.1 Overview
3.2.2 Product Portfolio
3.2.3 Target Customers
3.2.4 Key Personnel
3.2.5 Analyst View

• Tarsus Pharmaceuticals
• Valeant Pharmaceuticals International, Inc (Nicox Ophthalmics)
• Azura Ophthalmics
• Attillaps Pharmaceuticals

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