Protein Engineering Market To Grow At 16.27% CAGR By 2034, Driven By Rising Outsourcing And Expanding Healthcare Applications

2025-11-05 10:02:20

(MENAFN- GlobeNewsWire - Nasdaq) The global protein engineering market size is calculated at USD 3.58 billion in 2025 and is expected to reach around USD 13.84 billion by 2034, growing at a CAGR of 16.27% for the forecasted period.

Ottawa, Nov. 05, 2025 (GLOBE NEWSWIRE) -- The global protein engineering market

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Key Takeaways

North America held a major revenue share of the market in 2024.
Asia Pacific is expected to witness the fastest growth in the protein engineering market during the forecast period.
By product type, the instruments segment held a major revenue share of the market in 2024 and is expected to witness the fastest growth in the market during the forecast period.
By application type, the rational protein design segment held a major revenue share of the market in 2024.
By application type, the hybrid approach segment is expected to witness the fastest growth in the market during the forecast period.
By protein type, the monoclonal antibodies segment held a major revenue share of the market in 2024 and is expected to witness the fastest growth in the market during the forecast period.
By end user, the pharmaceutical & biotechnology companies segment held a major revenue share of the global protein engineering market in 2024.
By end user, the contract research organizations (CROs) segment is expected to witness the fastest growth in the market during the forecast period.

What is Meant by Protein Engineering?

The protein engineering market is driven by increasing demand for personalized medicines biologics

Key Metrics and Overview

Metric	Details
Market Size in 2024	USD 3.08 Billion
Projected Market Size in 2034	USD 13.84 Billion
CAGR (2025 - 2034)	16.27	%
Leading Region	North America
Market Segmentation	By Product, By Application, By Protein Type, By End-use and By Region
Top Key Players	Thermo Fisher Scientific, Inc., Agilent Technologies, PerkinElmer, Inc., Bruker Cor., Waters Corp., Amgen, Inc., Genscript Biotech Corp.

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What are the Major Growth Drivers in the Protein Engineering Market?

The growing R&D is the major growth driver in the market, which is increasing the use of protein engineering for drug discovery and development

What are the Key Drifts in the Protein Engineering Market?

The market has been expanding due to the growing funding and grants to launch and enhance the use of protein engineering.

In June 2025, a total of $35 million in Series A funding was announced to have been secured by Portal Biotech. This funding will be utilized for expansion of the engineering, data-science, and R&D teams, as well as for fast-track Portal Biotech's commercialization roadmap and strengthen the partnerships with leading pharmaceutical and biotech innovators.
In September 2025, a grant was awarded by the National Science Foundation Directorate for Technology, Innovation and Partnerships (NSF TIP), which is a part of a $32 million investment in protein engineering and AI to the University of California, Davis, for its 2 projects, which involve the use of AI in designing and engineering proteins for health and industrial applications.
In May 2025, a total of 210 million JPY in Series A extension funding was secured by RevolKa Ltd., which is a venture-backed biotech company providing a cutting-edge AI-driven protein engineering technology platform called aiProtein^®. Moreover, the funding will be utilized to support its drug discovery programs for rare diseases and collaborations.

What is the Significant Challenge in the Protein Engineering Market?

Technological complexities act as the major challenge in the market. This, in turn, increases the chances of errors leading to failure of the product's development, which drives the demand for skilled personnel. Moreover, high cost, side effects, limited infrastructure, and regulatory hurdles are the other market limitations.

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Regional Analysis

Why did North America Dominate the Protein Engineering Market in 2024?

In 2024, North America captured the biggest revenue share in the market, due to the presence of robust industries, the investments in protein engineering increased, which enhanced their use in drug development. Additionally, the growth in the R&D activities in industries and institutions increased the utilization of advanced technologies and instruments to support protein engineering. Moreover, their growing collaboration and demand for personalized medicines and biologics also increased their use, which enhanced the market growth.

What Made Asia Pacific Grow Fastest in the Protein Engineering Market in 2024?

Asia Pacific is expected to host the fastest growth in the market during the forecast period, driven by the expanding industries that increase the protein engineering for enzymes, drugs

Segmental Insights

By Product Analysis

Why Did the Instruments Segment Dominate in the Protein Engineering Market in 2024?

By product type, the instruments segment led the market in 2024 and is expected to show the highest growth in the market during the predicted time, as they are important for protein engineering accuracy and reproducibility. At the same time, the growth in R&D activities and the demand for advanced analysis tools have also increased their use. Additionally, automated instruments were also used for their high-throughput screening.

By Application Analysis

Which Application Type Segment Held the Dominating Share of the Protein Engineering Market in 2024?

By application type, the rational protein design segment held the dominating share in the market in 2024, driven by its increased use in the development of targeted treatment approaches. This, in turn, increased their use in the development of stable and effective therapeutic proteins and enzymes. Moreover, it also helped in developing affordable products in a short period of time.

By application type, the hybrid approach segment is expected to show the fastest growth rate in the market during the predicted time. They are being used to enhance the accuracy of the proteins developed. Therefore, they are being used by the industries to develop therapeutic proteins, where they are enhancing the success rates.

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By Protein Analysis

What Made Monoclonal Antibodies the Dominant Segment in the Protein Engineering Market in 2024?

By protein type, the monoclonal antibodies segment led the market in 2024 and is expected to show the highest growth in the market during the upcoming years, due to their wide range of applications. Moreover, their targeted action provided high specificity, which in turn reduces the side effects. They were also used in the development of biologics, which contributed to the market growth.

By End-user Analysis

How did the Pharmaceutical & Biotechnology Companies Segment Dominated the Protein Engineering Market in 2024?

By end user, the pharmaceutical & biotechnology companies segment held the largest share of the market in 2024, driven by their high R&D activities. This, in turn, increased the use of protein engineering for the development of biologics or biosimilars

By end user, the contract research organizations (CROs) segment is expected to show the fastest growth rate in the market during the upcoming years. The growing collaborations and outsourcing trends are increasing the demand for protein engineering. The growing demand for advanced technologies for protein engineering and biologics is also contributing to the same.

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Recent Developments in the Protein Engineering Market

In March 2025, a proprietary E. coli expression system developed to deliver exceptional stability and high yield in the production of recombinant proteins and plasmid DNA, titled EffiX, was launched by WuXi Biologics.
In February 2025, for protein engineering, a new generative AI-driven methodology utilizing a specialized protein large language model (pLLM) for the prediction of the most effective protein variants was launched by Capgemini.
In January 2025, with the use of protein evolutionary workflows and advanced Artificial Intelligence (AI) based design platforms, new designer proteins engineered were launched by Bio-Techne.

Protein Engineering Market Key Players List

PerkinElmer, Inc.
Agilent Technologies
Thermo Fisher Scientific, Inc.
Amgen, Inc.
Bruker Cor.
Genscript Biotech Corp.
Danaher Corp.
Merck KGaA
Waters Corp.
Bio-Rad Laboratories

Segments Covered in The Report

By Product

Instruments
Reagents
Software & Services

By Application

Rational Protein Design
Directed Evolution
Hybrid Approach
De Novo Protein Design
Others

By Protein Type

Insulin
Monoclonal Antibodies
Vaccines
Growth Factors
Colony Stimulating Factors
Coagulation Factors
Interferon
Others

By End-use

Academic Research Institutes
Contract Research Organizations (CROs)
Pharmaceutical & Biotechnology Companies

By Region

North America

U.S.
Canada
Mexico
Rest of North America

South America

Brazil
Argentina
Rest of South America

Europe

Western Europe

Germany
Italy
France
Netherlands
Spain
Portugal
Belgium
Ireland
UK
Iceland
Switzerland
Poland
Rest of Western Europe

Eastern Europe

Austria
Russia & Belarus
Türkiye
Albania
Rest of Eastern Europe

Asia Pacific

China
Taiwan
India
Japan
Australia and New Zealand,
ASEAN Countries (Singapore, Malaysia)
South Korea
Rest of APAC

MEA

GCC Countries
Saudi Arabia
United Arab Emirates (UAE)
Qatar
Kuwait
Oman
Bahrain
South Africa
Egypt
Rest of MEA

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