Itacitinib Emerging Drug Insights And Market Forecasts, 2019-2032: An Orally Bioavailable Inhibitor Of Janus-Associated Kinase 1 (JAK1) With Potential Antineoplastic And Immunomodulating Activities

(MENAFN- PR Newswire) DUBLIN, Dec. 7, 2023 /PRNewswire/ -- The
"Itacitinib Emerging Drug Insight and market Forecast - 2032" report has been added to
ResearchAndMarkets's offering.

This
report provides comprehensive insights about itacitinib for Bronchiolitis Obliterans Syndrome (BOS) in the seven major markets. A detailed picture of the itacitinib for bronchiolitis obliterans syndrome in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the itacitinib for bronchiolitis obliterans syndrome.

The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the itacitinib market forecast analysis for bronchiolitis obliterans syndrome in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in bronchiolitis obliterans syndrome.
Drug Summary
Itacitinib (also known as INCB-039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic and immunomodulating activities. Upon oral administration, itacitinib selectively inhibits JAK-1, thereby inhibiting the phosphorylation of signal transducer and activator of transcription (STAT) proteins and the production of pro-inflammatory factors induced by other cytokines, including interleukin-23 (IL-23) and interleukin-6 (IL-6).

The JAK-STAT pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.
Itacitinib Analytical Perspective

In-depth Itacitinib Market Assessment
This report provides a detailed market assessment of itacitinib for bronchiolitis obliterans syndrome in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2031 to 2032.
Itacitinib Clinical Assessment
The report provides the clinical trials information of itacitinib for bronchiolitis obliterans syndrome covering trial interventions, trial conditions, trial status, start and completion dates.
Report Highlights

• In the coming years, the market scenario for bronchiolitis obliterans syndrome is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence itacitinib dominance.
• Other emerging products for bronchiolitis obliterans syndrome are expected to give tough market competition to itacitinib and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of itacitinib in bronchiolitis obliterans syndrome.
• This in-depth analysis of the forecasted sales data of itacitinib from 2031 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the itacitinib in bronchiolitis obliterans syndrome.

Key Topics Covered:
1. Report Introduction
2. Itacitinib Overview in Bronchiolitis Obliterans Syndrome
2.1. Product Detail
2.2. Clinical Development
2.2.1. Clinical studies
2.2.2. Clinical trials information
2.2.3. Safety and efficacy
2.3. Product Profile
3. Competitive Landscape (Late-stage Emerging Therapies)
4. Itacitinib Market Assessment
4.1. Market Outlook of Itacitinib in Bronchiolitis Obliterans Syndrome
4.2. 7MM Analysis
4.2.1. Market Size of Itacitinib in the 7MM for Bronchiolitis Obliterans Syndrome
4.3. Country-wise Market Analysis
4.3.1. Market Size of Itacitinib in the United States for Bronchiolitis Obliterans Syndrome
4.3.2. Market Size of Itacitinib in Germany for Bronchiolitis Obliterans Syndrome
4.3.3. Market Size of Itacitinib in France for Bronchiolitis Obliterans Syndrome
4.3.4. Market Size of Itacitinib in Italy for Bronchiolitis Obliterans Syndrome
4.3.5. Market Size of Itacitinib in Spain for Bronchiolitis Obliterans Syndrome
4.3.6. Market Size of Itacitinib in the United Kingdom for Bronchiolitis Obliterans Syndrome
4.3.7. Market Size of Itacitinib in Japan for Bronchiolitis Obliterans Syndrome
5. SWOT Analysis
6. Analysts' Views
7. Appendix
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