Study Reveals How Pancreatic Tumors Evade Immunotherapy
Washington: Researchers at the Icahn School of Medicine at Mount Sinai have discovered that pancreatic cancer cells hijack blood-clotting mechanisms to block immune attacks, according to Medical Xpress.
The study shows that certain cancer cells produce proteins triggering a build-up of fibrin, the body's wound-healing substance, around the tumor. This creates a barrier against immune cells, with even a small number of cancer cells sufficient to shield the entire tumor.
Preclinical trials revealed that disrupting this fibrin barrier or blocking its interactions slowed tumor growth and significantly boosted immunotherapy effectiveness, opening new avenues for targeted cancer treatments.
Legal Disclaimer:
MENAFN provides the
information “as is” without warranty of any kind. We do not accept any
responsibility or liability for the accuracy, content, images, videos,
licenses, completeness, legality, or reliability of the information
contained in this article. If you have any complaints or copyright issues
related to this article, kindly contact the provider above.
Comments
No comment