Foresight Diagnostics And Partners To Present Independent Validation Data For Its CLARITYTM MRD Assay At The 2025 European Hematology Association (EHA) Congress And International Conference On Malignant Lymphoma (ICML)

(MENAFN- PR Newswire)

- Data will be presented as an oral presentation at EHA on Thursday, June 12, 2025, and at ICML on Thursday, June 19, 2025

BOULDER, Colo., June 10, 2025 /PRNewswire/ -- Foresight Diagnostics, a leading developer of ultra-sensitive minimal residual disease (MRD) detection technologies, today announced that validation data demonstrating the prognostic performance of its CLARITYTM MRD assay in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL) will be featured as encore oral presentations at two upcoming international conferences: the 2025 European Hematology Association (EHA) Congress (June 12–15, in Milan, Italy) and the 18th International Conference on Malignant Lymphoma (ICML) (June 17–21, in Lugano, Switzerland).

This multi-center study, conducted in collaboration with Amsterdam University Medical Centers, the Hemato-Oncology Foundation for Adults in the Netherlands (HOVON), and the Netherlands Comprehensive Cancer Organization (IKNL), highlights real-world results using Foresight CLARITYTM MRD on patients who were treated with frontline chemotherapy across over 50 centers in the Netherlands and Belgium.

"We're grateful to present our data at major medical meetings this spring, validating our science and the real-world utility of ultra-sensitive ctDNA-MRD technology," said David Kurtz, M.D., Ph.D., Chief Medical Officer of Foresight Diagnostics. "These presentations and the recent incorporation of ctDNA-MRD testing in B-cell lymphoma clinical guidelines give us confidence as we prepare to launch in the clinical market in 2026 and integrate Foresight CLARITY into routine clinical practice."

Lead study authors Steven Wang, M.D., and Martine Chamuleau, M.D., Ph.D., Amsterdam UMC, added: "Our findings confirm that ultra-sensitive ctDNA-MRD detection provides meaningful prognostic information beyond standard imaging and clinical factors. We believe this assay can support better risk stratification than imaging alone and inform post-treatment management decisions in DLBCL."

Oral presentation details for EHA:

• Title : Prospective validation of end of treatment ctDNA-MRD by PhasED-Seq in DLBCL patients from a national trial
  Presenter: Martine Chamuleau, MD, PhD (Amsterdam UMC)
  Session: Aggressive Non-Hodgkin lymphoma - Clinical (Observational)
  Time: Thursday, June 12 | 5:00 p.m. – 5:15 p.m. CEST / 11:00 a.m. – 11:15 a.m. ET
  Room: Brown Hall 3
  Abstract number: S240

Oral presentation details for ICML:

• Title : Prospective validation of end of treatment ctDNA-MRD by PhasED-Seq in DLBCL patients from a national HOVON trial
  Presenter: Martine Chamuleau, MD, PhD (Amsterdam UMC)
  Session: Session 6: Liquid biopsy for response assessment
  Time: Thursday, June 19 | 2:15 p.m. – 2:30 p.m. CEST / 8:15 a.m. – 8:30 a.m. ET
  Room: Polivalente room, East Campus USI
  Article number: 041

In addition to the oral presentation, Foresight's technology will be highlighted in other presentations, including:

• Title: Prognostic Value of Circulating Tumor DNA (ctDNA) Detection by PhasED-Seq After Axicabtagene ciloleucel (Axi-cel) Therapy in Relapsed/Refractory Large B-Cell Lymphoma (LBCL)
  Meeting: EHA 2025
  Sponsor: Kite Pharma
  Presenter: Jeffrey Gregg, MD (Foresight Diagnostics)
  Session: Poster Session I | Poster Hall
  Date/Time: Friday, June 13 | 6:30 p.m. – 7:30 p.m. CEST / 12:30 p.m. – 1:30 p.m. ET
  Abstract: #PF1002
  
• Title: The Correlation of Mutational Profiles and Valemetostat Efficacy in Patients With R/R PTCL in the Phase 2 VALENTINE-PTCL01 Tria
  Meeting: ICML 2025
  Sponsor: Daiichi Sankyo
  Presenter: Pier Luigi Zinzani, MD, PhD (University of Bologna)
  Session: "Focus On" Session Biology and Therapy of T-cell Lymphomas | Room B
  Date/Time: Saturday, June 14 | 10:05 a.m. – 10:15 a.m. CEST / 4:05 a.m. – 4:15 a.m. ET
  Article Number: 164

About Foresight Diagnostics

Foresight Diagnostics is a privately held cancer diagnostics company and CLIA-registered laboratory. Its liquid biopsy platform, Foresight CLARITYTM, is a novel assay that measures minimal residual disease (MRD) with reported detection limits in parts per million. The improved sensitivity of Foresight CLARITYTM has the potential to provide actionable information to physicians and biopharmaceutical companies to enable personalized treatment approaches for patients with solid tumor and hematologic malignancies. For more information, please visit foresight-dx and follow us on X , LinkedIn , and Bluesky .

SOURCE Foresight Diagnostics, Inc.

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